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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">sapi</journal-id><journal-title-group><journal-title xml:lang="ru">Системный анализ и прикладная информатика</journal-title><trans-title-group xml:lang="en"><trans-title>«System analysis and applied information science»</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2309-4923</issn><issn pub-type="epub">2414-0481</issn><publisher><publisher-name>Belarusian National Technical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21122/2309-4923-2022-4-65-72</article-id><article-id custom-type="elpub" pub-id-type="custom">sapi-596</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обработка информации и принятие решений</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Data processing and decision–making</subject></subj-group></article-categories><title-group><article-title>Регистрация дерматоскопических изображений новообразований кожи и выявление структурных отличий</article-title><trans-title-group xml:lang="en"><trans-title>Registration of dermatoscopic images of skin neoplasms and detection of structural differences</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смалюк</surname><given-names>А. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Smalyuk</surname><given-names>A. F.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Phd. Leading Scientist of the Research Laboratory of Mechanics of Materials and Dynamics of Technical Systems</p></bio><email xlink:type="simple">dsmsm@bntu.by</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жуковец</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukovets</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD. Head of the Department of Oncology</p></bio><email xlink:type="simple">zhukavets@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тризна</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Trizna</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD. Head of the Department (Minimally Invasive Surgery) Day Care, Associate Professor</p></bio><email xlink:type="simple">triznachka@gmail.co</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Белорусский национальный технический университет</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>Belarusian National Technical University</institution><country>Belarus</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Белорусская медицинская академия последипломного образования</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>Belarusian Medical Academy of Postgraduate Education</institution><country>Belarus</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Республиканский научно-практический центр онкологии и медицинской радиологии им. Н.Н. Александрова</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>N. N. Alexandrov National Cancer Centre of Belarus</institution><country>Belarus</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>24</day><month>02</month><year>2023</year></pub-date><volume>0</volume><issue>4</issue><fpage>65</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Смалюк А.Ф., Жуковец А.Г., Тризна Н.М., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Смалюк А.Ф., Жуковец А.Г., Тризна Н.М.</copyright-holder><copyright-holder xml:lang="en">Smalyuk A.F., Zhukovets A.G., Trizna N.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://sapi.bntu.by/jour/article/view/596">https://sapi.bntu.by/jour/article/view/596</self-uri><abstract><p>Рассмотрено применение алгоритма определения структурных различий на основе морфологического проектора для сравнения дерматоскопических изображений. Это позволит выявлять изменения, произошедшие в новообразованиях кожи с течением времени, для более точной диагностики их злокачественности. Предлагаемый алгоритм позволяет выявить различия в изображениях при наличии существенной разницы в яркости и цветовой гамме сравниваемых изображений, а также не учитывать мелкие несущественные детали, такие, как шум, метки оптики дерматоскопа, волосы и т.д.Также рассмотрена методика корректировки рассинхронизации полученных в разное время изображений, использующая индекс структурного сходства в качестве метрики подобия, и алгоритм синусов-косинусов в качестве оптимизационного. Проведено тестирование предлагаемых алгоритмов на дерматоскопических изображениях и продемонстрирован возможность их применения.</p></abstract><trans-abstract xml:lang="en"><p>The paper considers the application of an algorithm based on a morphological projector for determining structural differences for comparing dermoscopic images. This will allow to identify changes that have occurred in skin lesions over time, for a more accurate diagnosis of their malignancy. The proposed algorithm makes it possible to detect differences in images even if there is a significant difference in the brightness and color levels of the compared images, and also ignores small insignificant details, such as noise, dermatoscope optics marks, hair, etc. A method for correcting the desynchronization of images using the structural similarity index as a similarity metric, and the sinecosine algorithm as an optimization algorithm is proposed. The proposed algorithms were tested on dermatoscopic images and the possibility of their application was demonstrated.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>меланома</kwd><kwd>новообразование кожи</kwd><kwd>дерматоскоп</kwd><kwd>структурное различие</kwd><kwd>морфологический    проектор</kwd><kwd>метрика подобия</kwd><kwd>оптимизационный алгоритм</kwd></kwd-group><kwd-group xml:lang="en"><kwd>melanoma</kwd><kwd>skin lesion</kwd><kwd>dermatoscope</kwd><kwd>structural differences</kwd><kwd>morphological projector</kwd><kwd>similarity metric</kwd><kwd>optimization algorithm</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rigel DS, Russak J, Friedman R. The evolution of melanoma diagnosis: 25 years beyond the ABCDs. CA Cancer J Clin. 2010 Sep-Oct;60(5):301-16.</mixed-citation><mixed-citation xml:lang="en">Rigel DS, Russak J, Friedman R. 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